
Be Gentle With the Fourth Trimester: A Compassionate Guide to Healing Depression in Pregnancy and Postpartum

A Message to Every Mother Reading This
If you’ve found your way to this article, you might be wondering whether the heaviness you’re feeling is “normal” or something more. Perhaps you’re struggling to find joy in moments you expected to be magical, or maybe you’re questioning whether you’re the mother you thought you’d be.
First, let me tell you this: you are not alone, you are not broken, and you are not failing.
What you might be experiencing is perinatal depression—one of the most common complications of pregnancy and the postpartum period. And while that might feel overwhelming to consider, I want you to know that it’s also one of the most treatable.

Why We Must Talk About This Reality
The statistics tell a story that too many families face in silence: one in seven pregnant or newly-delivered mothers will experience a depressive episode.¹ That’s millions of women each year who find themselves struggling with more than just the expected challenges of new motherhood.
When perinatal depression goes untreated, the ripple effects extend far beyond the mother herself. Research shows increased risks of suicide (tragically, the leading cause of maternal death), preterm birth, difficulties with mother-baby bonding, and later behavioral challenges in children.²
But here’s what I want you to understand: seeking help for your mental health isn’t just about you—it’s one of the most important things you can do for your baby and your family.
Taking care of your emotional well-being is taking care of two or more lives. There’s nothing selfish about that—it’s essential.
Understanding the Difference: Baby Blues vs. Clinical Depression
Many new mothers experience what we call the “baby blues”—a brief period of emotional adjustment that’s completely normal. The baby blues typically:
- Peak around days 3-5 after delivery
- Include tearfulness but with moments of genuine joy still present
- Resolve naturally within two weeks
- Don’t significantly interfere with daily functioning
Clinical depression, however, looks different and requires professional support. Please reach out for help if you’re experiencing:
Persistent Emotional Symptoms
- Sadness, anxiety, or emptiness that doesn’t lift
- Loss of interest in activities you once enjoyed
- Overwhelming guilt, shame, or feelings of worthlessness
- Intense irritability or anger
Physical and Cognitive Changes
- Difficulty sleeping even when the baby sleeps
- Significant changes in appetite or energy
- Trouble concentrating or making decisions
- Physical aches without clear cause
Concerning Thoughts
- Thoughts of harming yourself
- Worries about harming your baby
- Feeling like your family would be better off without you
If these symptoms persist for more than two weeks, please know that help is available and recovery is absolutely possible.
Your Comprehensive Treatment Toolkit
Healing from perinatal depression isn’t one-size-fits-all. The most effective approach often combines several evidence-based strategies tailored to your unique situation, preferences, and severity of symptoms.
Evidence-Based Treatment Options
| Treatment Approach | Best For | What to Expect | Important Notes |
| Therapy (IPT/CBT) | Mild to moderate depression; first-line treatment | Weekly sessions to address thought patterns and relationships | 60% response rate; online options work nearly as well as in-person³ |
| Exercise | Prevention and treatment at any stage | 150 minutes/week moderate activity (walking, prenatal yoga, swimming) | Reduces depression risk by ~45%; always check with your OB first⁴ |
| Mindfulness Programs | Stress, rumination, sleep difficulties | 8-week guided meditation courses | Mobile programs show lasting benefits for up to 6 months⁵ |
| Bright Light Therapy | Seasonal depression, severe morning fatigue | 30 minutes/morning with 10,000 lux light box | Early research shows doubled remission rates⁶ |
| Nutritional Support | Foundation for all treatment approaches | Mediterranean-style eating, omega-3s, vitamin monitoring | Deficiencies worsen outcomes; supplements alone don’t treat depression⁷ |
| Medication | Moderate to severe depression, when therapy isn’t enough | SSRIs/SNRIs with strong safety profiles in pregnancy/breastfeeding | Small increase in temporary newborn adjustment issues; no increase in birth defects⁸ |
| Novel Biologics | Severe, rapid-onset postpartum depression | IV brexanolone or oral zuranolone | Fast response (≤3 days) but requires specialized monitoring |
Medication and Breastfeeding: What You Need to Know
I understand that considering medication while pregnant or breastfeeding can feel overwhelming. Medication is one of many treatment options and sometimes it is an important option. Many mothers worry about potential risks to their babies, and these concerns are completely valid and understandable.
Here’s what the research tells us:
During Pregnancy
- Untreated depression often poses greater risks than medication
- Certain medications (like sertraline, citalopram, escitalopram) have extensive safety data
- We always use the lowest effective dose
- Close monitoring ensures the best outcomes for both you and baby
During Breastfeeding
- Most antidepressants transfer into breast milk in very small amounts
- The benefits of breastfeeding typically outweigh minimal medication exposure
- Your pediatrician will monitor your baby’s growth and development as usual
Practical Breastfeeding Tips if You Take Medication:
- Time your medication dose right after nursing when possible
- Peak milk levels occur about 4 hours after most SSRIs
- Watch for changes in baby’s sleep, feeding, or weight gain
- Preterm or medically fragile infants may need closer observation
Remember: The goal is a healthy mother and a healthy baby. Sometimes medication is the path to both.
Gentle Steps You Can Start Today
While professional treatment is often essential, there are nurturing steps you can take right now to support your mental health:
Honor Your Need for Rest
- Aim for one uninterrupted 4-hour sleep stretch when possible
- Trade night feedings with your partner or support person
- Rest when the baby rests, even if you can’t sleep
- Remember: the dishes can wait, but your well-being cannot
Nourish Your Body Mindfully
- Keep nutrient-dense snacks within arm’s reach of your nursing chair
- Try trail mix, Greek yogurt, cut fruit, or whole grain crackers
- Stay hydrated—dehydration worsens mood and energy
- Be gentle with yourself about “perfect” eating
Move Your Body Gently
- Take stroller walks around the block
- Try 10-minute yoga flows or stretching sessions
- Dance with your baby to music you love
- Remember: any movement counts
Connect with Your Village
- Join online communities like MomMoodBooster when in-person groups feel impossible
- Video call friends and family regularly
- Consider app-based therapy if traditional appointments are challenging
- Remember: asking for help is a sign of strength, not weakness
When to Reach Out for Professional Help
Please don’t wait until you’re in crisis to seek support. Reach out if you’re experiencing:
Screening Score Concerns
- Edinburgh Postnatal Depression Scale (EPDS) score of 13 or higher
- Patient Health Questionnaire (PHQ-9) score of 10 or higher
Daily Functioning Challenges
- Inability to sleep or eat for more than 24 hours
- Difficulty caring for yourself or your baby
- Persistent thoughts of self-harm or harming your baby
Emergency Situations
- Hearing voices or having unusual beliefs
- Plans to hurt yourself or your baby
- Feeling completely disconnected from reality
If you’re experiencing psychotic symptoms, please go to the emergency room immediately. This is a medical emergency that requires immediate professional care.
My Approach to Perinatal Mental Health
In my practice, I understand that seeking help as a new or expecting mother comes with unique challenges. That’s why I’ve created a space where:
Babies Are Always Welcome
- Crying babies don’t interrupt sessions—they’re part of life
- I provide a comfortable, judgment-free environment for nursing mothers
- Virtual sessions available when leaving home feels impossible
Integrated, Collaborative Care
- I coordinate closely with your OB/GYN, lactation consultant, and pediatrician
- Comprehensive approach combining medication management and therapeutic support
- Both in-person and telehealth options available
Individualized Treatment Plans
- I meet you where you are in your journey
- Treatment plans that respect your values, preferences, and circumstances
- Ongoing adjustments based on your response and changing needs
A Message of Hope
Dear mother, if you’re struggling right now, I want you to know that perinatal depression is:
Common — You are far from alone in this experience
Treatable — With proper support, the vast majority of mothers recover fully
Not your fault — Depression is a medical condition, not a personal failing
Temporary — With treatment, you can and will feel like yourself again
Your children need you healthy and whole. Your family needs you present and thriving. Most importantly, you deserve to feel joy in this journey of motherhood.
Recovery is not just possible—with early intervention, evidence-based treatment, and compassionate support, it’s expected. Both you and your children can emerge from this experience stronger and more connected.
You are a good mother. You are worthy of help. You are going to be okay.
With deep compassion and unwavering support,
Dr. Beata Lewis
Crisis Resources
If you’re in immediate danger:
- Call 911 or go to your nearest emergency room
- Call 988 (Suicide & Crisis Lifeline)
- Text “HOME” to 741741 (Crisis Text Line)
For ongoing support:
- Postpartum Support International: 1-800-944-4773
- Text “HELP” to PSI at 800-944-4773
- Dr. Lewis: www.drlewis.com
Remember: Reaching out for help is an act of love—for yourself and your family.
References
- Justesen, K., & Jourdaine, D. (2023). Peripartum depression: Detection and treatment. American Family Physician, 108(3), 267–272.
https://pubmed.ncbi.nlm.nih.gov/37725459
- Stewart, D. E., & Vigod, S. (2016). Postpartum depression. The New England Journal of Medicine, 375(22), 2177–2186. https://doi.org/10.1056/NEJMcp1607649
- Hankin, B. L., et al. (2023). Effect of brief interpersonal therapy on depression during pregnancy: A randomized clinical trial. JAMA Psychiatry, 80(6), 539–547. https://doi.org/10.1001/jamapsychiatry.2023.0702
- Liu, X., Wang, G., & Cao, Y. (2022). Physical exercise interventions for perinatal depression symptoms in women: A meta-analysis. Frontiers in Psychology, 13, 1022402. https://doi.org/10.3389/fpsyg.2022.1022402
- Leng, L. L., et al. (2023). Antenatal mobile-delivered mindfulness-based intervention… Journal of Affective Disorders, 335, 216–227. https://doi.org/10.1016/j.jad.2023.04.133
- Chen, Y., et al. (2024). Effect of bright light therapy on perinatal depression: A meta-analysis. Canadian Journal of Psychiatry, 69(10), 737–748. https://doi.org/10.1177/07067437241248051
- Mocking, R. J. T., et al. (2020). Omega-3 fatty acid supplementation for perinatal depression: A meta-analysis. The Journal of Clinical Psychiatry, 81(5), 19r13106. https://doi.org/10.4088/JCP.19r13106
Brown, J. V. E., et al. (2021). Antidepressant treatment for postnatal depression. Cochrane Database of Systematic Reviews, 2, CD013560. https://doi.org/10.1002/14651858.CD013560.pub2





